Seiler, J., & Beye, M. (2024). Honeybees' novel complementary sex-determining system: function and origin. Trends in genetics : TIG, 40(11), 969–981. https://doi.org/10.1016/j.tig.2024.08.001
Sommer, V., Seiler, J., Sturm, A., Köhnen, S., Wagner, A., Blut, C., Rössler, W., Goodwin, S. F., Grünewald, B., & Beye, M. (2024). Dedicated developmental programing for group-supporting behaviors in eusocial honeybees. Science advances, 10(44), eadp3953. https://doi.org/10.1126/sciadv.adp3953
Otte, M., Netschitailo, O., Weidtkamp-Peters, S., Seidel, C.A.M., and Beye, M. (2023). Recognition of polymorphic Csd proteins determines sex in the honeybee. https://www.science.org/doi/10.1126/sciadv.adg4239
Netschitailo, O., Wang, Y., Wagner, A., Sommer, V., Verhulst, E.C., and Beye, M. (2023). The function and evolution of a genetic switch controlling sexually dimorphic eye differentiation in honeybees. Nature communications 14, 463.
Carcaud, J., Otte, M., Grunewald, B., Haase, A., Sandoz, J.C., and Beye, M. (2023). Multisite imaging of neural activity using a genetically encoded calcium sensor in the honey bee. PLoS biology 21, e3001984.
Wagner, A., Seiler, J., and Beye, M. (2022). Highly efficient site-specific integration of DNA fragments into the honeybee genome using CRISPR/Cas9. G3 (Bethesda) 12. 10.1093/g3journal/jkac098.
Netschitailo, O., Raub, S., Kaftanoglu, O., and Beye, M. (2022). Sexual diversification of splicing regulation during embryonic development in honeybees (Apis mellifera), A haplodiploid system. Insect Mol Biol 31, 170-176. 10.1111/imb.12748.
Degirmenci, L., Geiger, D., Roge Ferreira, F.L., Keller, A., Krischke, B., Beye, M., Steffan-Dewenter, I., and Scheiner, R. (2020). CRISPR/Cas 9-Mediated Mutations as a New Tool for Studying Taste in Honeybees. Chem Senses 45, 655-666. 10.1093/chemse/bjaa063.
Roth, A., Vleurinck, C., Netschitailo, O., Bauer, V., Otte, M., Kaftanoglu, O., Page, R.E., and Beye, M. (2019). A genetic switch for worker nutrition-mediated traits in honeybees. PLoS biology 17, e3000171. 10.1371/journal.pbio.3000171.
Otte, M., Netschitailo, O., Kaftanoglu, O., Wang, Y., Page, R.E., Jr., and Beye, M. (2018). Improving genetic transformation rates in honeybees. Sci Rep 8, 16534. 10.1038/s41598-018-34724-w.
Koch, V., Otte, M., and Beye, M. (2018). Evidence for Stabilizing Selection Driving Mutational Turnover of Short Motifs in the Eukaryotic Complementary Sex Determiner (Csd) Protein. G3 (Bethesda) 8, 3803-3812. 10.1534/g3.118.200527.
Blut, C., Crespi, A., Mersch, D., Keller, L., Zhao, L., Kollmann, M., Schellscheidt, B., Fulber, C., and Beye, M. (2017). Automated computer-based detection of encounter behaviours in groups of honeybees. Sci Rep 7, 17663. 10.1038/s41598-017-17863-4.
Vleurinck, C., Raub, S., Sturgill, D., Oliver, B., and Beye, M. (2016). Linking Genes and Brain Development of Honeybee Workers: A Whole-Transcriptome Approach. PloS one 11, e0157980. 10.1371/journal.pone.0157980.
Gempe, T., Stach, S., Bienefeld, K., Otte, M., and Beye, M. (2016). Behavioral and molecular studies of quantitative differences in hygienic behavior in honeybees. BMC Res Notes 9, 474. 10.1186/s13104-016-2269-y.
Sadd, B.M., Barribeau, S.M., Bloch, G., de Graaf, D.C., Dearden, P., Elsik, C.G., Gadau, J., Grimmelikhuijzen, C.J., Hasselmann, M., Lozier, J.D., et al. (2015). The genomes of two key bumblebee species with primitive eusocial organization. Genome biology 16, 76. 10.1186/s13059-015-0623-3.
Schulte, C., Theilenberg, E., Müller-Borg, M., Gempe, T. & Beye, M. (2014). "Highly efficient integration and expression of piggyBac-derived cassettes in the honeybee (Apis mellifera)." PNAS 11 (24) 9003-9008PDF
Koch, V., Nissen, I., Schmitt, B.D. & Beye, M. (2014). "Independent evolutionary origin of fem paralogous genes and complementary sex determination in hymenopteran insects." PLoS ONE 9(4): e91883PDF
Schulte, C., Leboulle, G., Otte, M., Grunewald, B., Gehne, N. & Beye, M. (2013). "Honey bee promoter sequences for targeted gene expression." Insect Mol Biol 22(4): 399-410PDF
Beye, M., Seelmann, C., Gempe, T., Hasselmann, M., Vekemans, X., Fondrk, K. & Page, R.E. (2013). "Gradual molecular evolution of a sex determination switch through incomplete penetrance of femaleness." Current Biology 23(24) 2559–2564PDF
Nissen, I., Müller, M. & Beye, M. (2012). "The Am-tra2 gene is an essential regulator of female splice regulation at two levels of the sex determination hierarchy of the honeybee." Genetics 192:1015-1026PDF
Gempe, T., Stach, S., Bienefeld, K. & Beye, M. (2012). "Mixing of honeybees with different genotypes affects individual worker behavior and transcription of genes in the neuronal substrate." PLoS ONE 7(2): e31653PDF
Gempe, T. & Beye, M. (2011). "Function and evolution of sex determination mechanisms, genes and pathways in insects." Bioessays 33, 52-60PDF
Hasselmann, M., Lechner, S., Schulte, C. & Beye, M. (2010). "Origin of a function by tandem gene duplication limits the evolutionary capability of its sister copy gene." PNAS 107 (30) 13378-13383PDF
Gempe, T., Hasselmann, M., Schiøtt M., Hause, G., Otte, M. & Beye, M. (2009). "Sex determination in honeybees: Two separate mechanisms induce and maintain the female pathway." PloS Biology 7(10): e1000222PDF
Hasselmann, M., Gempe, T., Schiøtt, M., Nunes-Silva, C.-G., Otte, M. & Beye, M. (2008). "Evidence for the evolutionary nascence of a novel sex determination pathway in honey bees." Nature 454: 519-522PDF
Hasselmann, M., Vekemans, X., Pflugfelder, J., Koeniger, N., Koeniger, G., Tingek, S. & Beye, M. (2008). "Evidence for convergent nucleotide evolution and high allelic turnover rates at the complementary sex determiner (csd) gene of western and asian honey bees." Molecular Biology and Evolution 25(4): 696-708PDF
Hasselmann, M. & Beye, M. (2006). "Pronounced differences of recombination activity at the sex determination locus (SDL) of the honey bee, a locus under strong balancing selection." Genetics 174: 1469-1480PDF
Beye, M., Gattermeier, I., Hasselmann, M., Gempe, T., Schioett, M., Baines, J., Schlipalius, D., Florence, M., Emore, C., Rueppell, O., Sirviö, A., Guzmán-Novoa, E., Hunt, G., Solignac, M. & Page, R.E. (2006). "Exceptionally high levels of recombination across the honey bee genome." Genome Research 16: 1339-1344PDF
Dearden, P.K., Wilson, M.J., Sablan, L., Osborne, P.W., Havler, M., McNaughton, E., Kimura, K., Milshina, N.V., Hasselmann, M., Gempe, T., Schioett, M., Brown, S.J., Elsik, C.G., Holland, P.W.H., Kadowaki, T. & Beye, M. (2006). "Patterns of conservation and change in honey bee developmental genes." Genome Research 16: 1376-138PDF
Honey bee genome consortium (2006). "Insights into social insects from the genome of the honey bee Apis mellifera". Nature 473: 931-949PDF
Beye, M. (2004). "The dice of fate: the csd gene and how its allelic composition regulates sexual development in the honey bee, Apis mellifera." BioEssays 26 (10): 1131-1139PDF
Hasselmann, M. & Beye, M. (2004). "Signatures of selection among sex-determining alleles of the honey bee." PNAS 101 (14): 4888-4893PDF
Rüppell, O., Pankiw, T., Nielsen, D.I., Fondrk, M.K., Beye, M. & Page Jr. R.E. (2004). "The genetic architecture of the behavioral ontogeny of honey bee workers." Genetics 167, 1767-1769PDF
Beye, M., Hasselmann, M., Fondrk, M.K., Page, R.E., & Omholt, S.W. (2003). "The gene csd is the primary signal for sexual development in the honey bee and encodes a SR-type protein." Cell 114, 419-429PDF
Beye, M., Härtel, S., Hagen, A., Hasselmann, M., & Omholt, S.W. (2002). "Specific developmental gene silencing in the honey bee using a homeobox motif." Insect. Mol. Biol. 11, 527-532PDF